THURSDAY 28 SEPTEMBER 2023
Sponsored and presented by SCIEX
Food allergies are the leading cause of anaphylaxis, an acute, potentially deadly allergic reaction. The prevalence and severity of food allergies are rising, with approximately 150 million people suffering from food allergies worldwide. Presently, there is no cure for food allergies, and sufferers must rely on the correct labeling of foods to avoid consuming allergens. Hence, developing sensitive and accurate analytical methods to screen for the presence of allergens in food products is necessary to prevent potentially life-threatening health problems for allergy sufferers.
The SCIEX vMethod applications for food allergen testing previously provided a workflow for sample preparation and LC-MS/MS detection of 12 distinct allergens, including egg, milk, almond, Brazil nut, cashew, hazelnut, pine nut, pistachio, pecan, walnut, peanut and soy, and for the quantification of gluten.
In 2021, the Food Allergy Safety, Treatment, Education, and Research (FASTER) Act was passed in the United States. The FASTER Act requires all foods sold in the United States that contain sesame to declare it as an ingredient or state “Contains: Sesame” immediately after the ingredient list. After evaluating 24 different sesame peptides, 2 of the most sensitive peptides were selected and added to the SCIEX vMethod.
In this workshop, applications experts from SCIEX discussed the challenges of developing and expanding the LC-MS/MS workflow and verifying it to the standards required to achieve its First Action Official Method (FAOM) classification from AOAC INTERNATIONAL.